Retinal AI Biomarkers for CNS Clinical Trials

Precision Patient Selection

Identify the right patients and reduce cohort variability using validated retinal biomarkers.

Capture structural CNS damage over time — even in “stable” patients — increasing statistical power.

Support better decision-making, reduce failure risk, and help therapies move through trials more efficiently.

Backed by 10+ years of data and 50,000+ scans across multiple centers, devices, and populations.

OCT analysis

Our technology combines complex image processing methods with mathematical 3D modeling to compute quantifiable parameters for the smallest disease-related changes in the retina’s shape. We call this 3D morphometry.

Retina Report

We provide a secure local installable web application, for standard  OCT scans. The analyzed data with Nocturne’s technology is provided in the form of a comprehensive report. Visual aids and explanations help users identify potential disease-related changes.

How does it work?