Understanding how the brain works is a major research challenge. The eye's retina is the only part of the brain that can be seen directly. It allows direct assessment of changes in the brain caused by neurological diseases. Nocturne has developed a range of methods and algorithms (patent pending), for reliable and precise measurements of retinal structural changes on standard OCT retina scans. We have the potential to offer a way to measure more accurate and fast specific changes for neurological applications.


Automatic quality analysis. It enables selection of high-quality OCT images, essential for accurate intra-retinal layer segmentation and quantification of small retinal layer changes, while considerably reducing the effort of manual check.




Intraretinal layer segmentation. It enables the measurement of different layer thicknesses. Numerous scientific publications prove the relevance of these measurements in neurological clinical studies.


Fovea morphometry. An innovative approach to analyze and model small shape changes of 3D macula volume scans, specific for neuroinflammatory disease.




Optic nerve head volume. An innovative algorithm for 3D quantification of occurring changes of the optic nerve head in the form of swelling (in case of inflammation) and atrophy (caused by degeneration).